Magnified 125x, this trichrome-stained photomicrograph of a brain tissue specimen depicts the cytoarchitectural changes associated with a free-living, Naegleria fowleri, amebic infection. When free-living amebae infect the brain or spinal cord, the condition is known as primary amebic meningoenceohalitis, or PAM. Free-living amebae belonging to the genera Acanthamoeba, Balamuthia, and Naegleria are important causes of disease in humans and animals, though only one specie of Naegleria, Naegleria fowleri, causes disease in humans.
December 2, 2012
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